# NAD+ and metabolic

1 paper in the library, strongest Preliminary.

**Graded Preliminary**: Cell studies with mouse, pig, and non-human primate models, yet the mechanism and the combined treatment have not been tested in people.

## Papers (1)

- [Why Low NAD+ May Push Insulin-Making Cells Into Self-Inflicted Inflammation](https://longevity-austria.com/en/research/why-low-nad-may-push-insulin-making-cells-into-self-inflicted-inflammation) · Preliminary · 2026 · Cell death and differentiation

## How this map is computed

A mark's size is the number of papers we hold on that pairing. It is a count, not a weighting by study design or sample size.

The fill shows the strongest grade in the cell. One Strong paper among four Preliminary ones still fills it dark, so open the cell to see the rest.

Grades and verdicts are assigned by a named person, never by counting.

An empty cell is a finding: nobody in our library has run that trial yet.

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_Canonical: https://longevity-austria.com/en/evidence/nad-precursors/metabolic · Part of Longevity Cities_