# Three Ways to Measure Biological Age All Predict Heart Disease

*The association of accelerated biological aging with heart diseases in adults aged 40-69 years: a population-based cohort study.*

- **Evidence Level**: Strong
- **Publication Types**: Journal Article
- **Journal**: Heart & lung : the journal of critical care
- **Sample Size**: 321,324 UK Biobank adults aged 40-69
- **Authors**: Wang R, Chen Y, Yin X, Wang X, Zan J, Zhang Y
- **Published**: 2026-04-29
- **Topics**: biological age, heart disease, aging clocks
- **DOI**: https://doi.org/10.1016/j.hrtlng.2026.102824
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/42061317/

## Summary

In over 320,000 UK adults followed for nearly 14 years, accelerated biological aging predicted heart trouble across the board. Depending on which aging clock was used, faster aging raised heart failure risk by 26% to 52% per standard deviation. Adding these biological age scores to standard risk models improved prediction of who would develop heart disease.

## Practical Takeaway

This study suggests biological age tests could complement standard cholesterol and blood pressure checks for heart risk.

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