45 studies
Research Library
Peer-reviewed papers from top journals, summarized and graded by evidence strength. Updated Mon, Wed & Fri.
Cholesterol, Immune Cells, and IGF-1 Emerge as Key Longevity Signals
Researchers combed through massive genetic databases to find what actually drives long life and slower biological aging. Three factors stood out: cholesterol levels, immune cell traits, and IGF-1 (a growth hormone linked to aging). They also flagged 30 genes and several proteins as possible drug targets for future anti-aging therapies.
New Aging Clocks Built From Histone Marks Work Across Species
Researchers built 36 new biological aging clocks using histone modifications (chemical tags on the proteins that package DNA) instead of the usual DNA methylation approach. These clocks worked well across six tissue types and could detect accelerated aging in leukemia samples and age reversal after treatments. One surprising finding: many aging-related changes peak at midlife rather than climbing steadily. The approach even worked in fruit flies, which lack DNA methylation entirely.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
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