Cohort Study (Preprint)bioRxiv : the preprint server for biology·Mar 2026
Red Blood Cell Proteins Can Track Biological Aging and Predict Health a Decade Later
Key Insight
This study suggests red blood cell proteins could serve as accessible markers of biological aging.
Researchers built a protein-based aging clock from the red blood cells of over 13,000 blood donors. People with conditions like G6PD deficiency and sickle cell trait showed accelerated molecular aging. Iron supplementation appeared to reverse some of that acceleration. The molecular age scores predicted real-world outcomes like hemolysis and donor activity over a 12-year follow-up.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
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