Metformin Added Nothing to Diet and Exercise for Older Adults' Strength
This study suggests structured exercise and diet drive physical function gains, not metformin.
Metformin has a big fan club in longevity circles, but this trial puts a dent in the hype. Older adults with obesity, aged 65 to 85, did six months of serious diet and exercise coaching. Adding metformin on top gave zero extra improvement in physical function compared to a placebo. The lifestyle program itself was what moved the needle.
Conflict of Interest Disclosure: None declared; funded by the US Department of Veterans Affairs.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Related Studies
All researchNot All Balance Training Is Equal: Which Exercises Work Best After 60
Looking at hundreds of trials in adults over 60, nearly every type of exercise improved balance.
For Older Muscle Quality, Lifting Weights Beat Supplements and Cardio
Looking at dozens of trials in adults over 60, resistance training was the only thing that clearly improved muscle quality (strength…
How Fast You Stand Up May Predict Your Lifespan Better Than Your Illnesses
Doctors usually judge older patients by their list of diagnoses.