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Journal ArticleRandomized Controlled TrialClinical Trial, Phase IIAlzheimer's & dementia : the journal of the Alzheimer's Association·Jul 2026

NAD+ Booster Raised Cellular Fuel But Didn't Improve Memory in 12 Weeks

Key Insight

This pilot suggests NR raises NAD+ but may not improve memory in mild cognitive impairment.


Nicotinamide riboside, a popular NAD+ supplement, doubled NAD+ levels in older adults with mild memory problems. But it did not improve their thinking, brain blood flow, or blood pressure over 12 weeks. There were hints of more blood flow in the memory region of the brain, but that needs more testing. It was safe and well tolerated.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.