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Journal ArticleMolecular biology reports·Jul 2026

NMN Protected Rat Testes From Chemotherapy Damage in Early Study

Key Insight

This early rat study hints NMN may protect against chemo-related testicular damage, but human effects are unproven.


The chemo drug doxorubicin badly damages the testes, a real worry for male cancer patients. In rats, the NAD+ booster NMN reduced this damage by lowering oxidative stress and protecting mitochondria. This is early animal work, and whether it protects fertility in humans is still unknown.

Conflict of Interest Disclosure: The authors declare no conflict of interest.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.