Old Blood Cells Turned Into Neural Stem Cells Shed Most of Their Epigenetic Age
Graded Preliminary — lab study of cells from donors aged 0 to 101 with no living subjects treated, so any relevance to whole-body aging is untested.
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Converting blood cells from older donors into neural stem cells erased most of their epigenetic age, the biological age that aging clocks measure. Working with cells from donors aged newborn to 101, the team found the new cells kept only 5 to 13 percent of donor age. The rewind was slow and unfolded over weeks, making this a useful model for studying how cells shed age. This is lab dish work, and it shows nothing yet about rejuvenating tissues in a living person.
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