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Journal ArticleInternational journal of molecular sciences·Jul 2026

Probiotics Plus Vitamin D Linked to Remission in a Painful Mouth Condition

Key Insight

This study suggests probiotics and vitamin D deserve testing for oral inflammation in larger controlled trials.


Oral lichen planus is a chronic inflammatory condition in the mouth that is hard to treat and carries a small cancer risk. In 25 mostly older adults, 16 weeks of a three-strain probiotic blend, plus vitamin D3 for those who were deficient, came with fewer and smaller lesions. About three quarters were rated as in remission, and gut and saliva chemistry shifted too. There was no control group, so we cannot say the supplements alone caused the improvement.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.