Which Interventions Actually Turn Back Your Epigenetic Clock in Humans
Graded Moderate — systematic review of 41 human intervention studies, though the clocks it tracks are still investigational biomarkers and the underlying trials varied widely in design.
- Design
- Review
- Participants
- 41
- Duration
- —
- Funding
- Authors are tied to longevity companies including Tally Health and several…
This review suggests exercise, omega-3s, and a plant-rich diet may lower epigenetic age in people.
Researchers gathered 41 human studies to see what really lowers your epigenetic age, the newer clocks tied to death risk. Exercise, a plant-rich diet, semaglutide, calorie cutting, omega-3s, and a multivitamin showed promise. But popular bets like nicotinamide riboside, rapamycin, and senolytics showed no measurable effect.
Conflict of Interest Disclosure: Authors are tied to longevity companies including Tally Health and several firms founded by David Sinclair.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
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