EGCG (Epigallocatechin gallate)

EGCG is the most abundant catechin in green tea and a polyphenol with antioxidant, anti-inflammatory, and AMPK-modulating activity. Observational data link green tea consumption to lower cardiovascular and all-cause mortality. Trials of EGCG supplements show small effects on lipids, blood pressure, and body weight, with high-dose extracts associated with hepatotoxicity in rare cases. Direct evidence for human longevity from isolated EGCG remains limited.